Article
Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive.
Journal of cell science - 1 Aug 2004
Romanova Larisa Y, Hashimoto Shigeru, Chay Kee-Oh, Blagosklonny Mikhail V, Sabe Hisataka, Mushinski J Frederic
Abstract excerpt
Tyrosine phosphorylation of paxillin regulates actin cytoskeleton-dependent changes in cell morphology and motility in adherent cells. In this report we investigated the involvement of paxillin tyrosine phosphorylation in the regulation of actin cytoskeleton-dependent polarization and motility of a non-adherent IL-3-dependent murine pre-B lymphocytic cell line Baf3. We also assessed the effect of phorbol...
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