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Article

BCL6 suppresses RhoA activity to alter macrophage morphology and motility.

Journal of cell science - 1 May 2005

Pixley Fiona J, Xiong Ying, Yu Raymond Yick-Loi, Sahai Erik A, Stanley E Richard, Ye B Hilda

Abstract excerpt

BCL6 is a potent transcriptional repressor that plays important roles in germinal center formation, T helper cell differentiation and lymphomagenesis and regulates expression of several chemokine genes in macrophages. In a further investigation of its role in macrophages, we show that BCL6 inactivation in primary bone marrow-derived macrophages leads to decreased polarization, motility and cell spreading...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15860730
DOI: 10.1242/jcs.02314

Genes

BCL6
RASA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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