Article
EphB1-mediated cell migration requires the phosphorylation of paxillin at Tyr-31/Tyr-118.
The Journal of biological chemistry - 2 Jul 2004
Vindis Cécile, Teli Thalia, Cerretti Douglas P, Turner Christopher E, Huynh-Do Uyen
Abstract excerpt
Interactions between Eph receptors and their membrane-bound ligands (ephrins) are of critical importance for key developmental processes such as boundary formation or vascular development. Their downstream signaling pathways are intricate and heterogeneous at several levels, the combined effect being a highly complex and flexible system. Here we demonstrate that activated EphB1 induces tyrosine phosphorylation of...
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