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Article

Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors.

Human gene therapy - 1 Aug 1992

Li M, Hantzopoulos P A, Banerjee D, Zhao S C, Schweitzer B I, Gilboa E, Bertino J R

Abstract excerpt

To determine the effect of different promoters on the expression of an altered dihydrofolate reductase (DHFR) gene conferring methotrexate (MTX) resistance in different cell types, double-copy retroviral vectors were constructed carrying a murine mutant DHFR under the control of five different promoters, i.e., human adenosine deaminase (ADA), simian virus 40 (SV40), thymidine kinase (TK), human beta-actin, and...

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Source

Identifiers

PMID: 1525211
DOI: 10.1089/hum.1992.3.4-381

Genes

DHFR
ADA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors.PMID 1525211Read ↗

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