Article
beta2 adrenoceptor Arg16Gly polymorphism, airway responsiveness, lung function and asthma in infants and children.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jul 2004
Turner S W, Khoo S-K, Laing I A, Palmer L J, Gibson N A, Rye P, Landau L I, Goldblatt J, Le Souëf P N
Abstract excerpt
BACKGROUND: We have previously reported a relationship between increased airway responsiveness (AR) in infancy and reduced childhood lung function. OBJECTIVE: The current study aimed to determine whether the Arg16Gly polymorphism of the beta2 adrenoceptor (beta2AR) gene was important to this relationship. METHODS: A cohort that initially numbered 253 individuals underwent assessments of AR and lung function aged...
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