Article
Polymorphism of the ADRB2 gene and response to inhaled beta- agonists in children with asthma: a meta-analysis.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Nov 2009
Finkelstein Yaron, Bournissen Facundo Garcia, Hutson Janine R, Shannon Michael
Abstract excerpt
BACKGROUND: About 9% of children have asthma, corresponding to almost 6.8 million children in the USA and 1.1 million in the UK. Asthma exacerbations are the leading cause of pediatric emergency room visits and impose a large burden on the individual, family, and society. There is mounting evidence that therapeutic failure of inhaled beta-agonists is associated with polymorphisms of the beta(2)-adrenergic...
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