Article
Polymorphisms in the beta2-adrenoreceptor gene are associated with decreased airway responsiveness.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 1999
Ramsay C E, Hayden C M, Tiller K J, Burton P R, Goldblatt J, Lesouef P N
Abstract excerpt
BACKGROUND: There are a number of candidate genes thought to play a role in the development of asthma. Polymorphisms at amino acid positions 16 (arginine to glycine) and 27 (glutamine to glutamic acid) of the beta2-adrenoreceptor (B2AR) gene are known to be functionally relevant and have been associated with more severe forms of asthma, nocturnal asthma and decreased airway responsiveness in asthmatic subjects....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.