Article
Association of haplotypes of beta2-adrenoceptor polymorphisms with lung function and airway responsiveness in a pediatric cohort.
Pediatric pulmonology - 1 Dec 2006
Zhang G, Hayden C M, Khoo S-K, Laing I A, Turner S, Landau L, Goldblatt J, Le Souëf P N
Abstract excerpt
We evaluated the influence of haplotypes of beta(2)-adrenergic receptor (ADRB2) polymorphisms on lung function and airway responsiveness (AR) in a pediatric cohort recruited before birth and followed up to 11 years of age. The subjects (180) were the participants in a prospective study of lung function and AR. They have been assessed five times (at 1 month, 6 months, 12 months, 6 and 11 years of age) for lung...
Topics
- Airway Resistance
- Asthma
- Child
- Child, Preschool
- Female
- Follow-Up Studies
- Forced Expiratory Volume
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Infant
- Infant, Newborn
- Male
- Polymorphism, Genetic