Article
B2 adrenergic receptor gene polymorphism effect on childhood asthma severity and response to treatment.
Pediatric research - 1 Mar 2018
Alghobashy Ashgan Abdallah, Elsharawy Sahar A, Alkholy Usama M, Abdalmonem Nermin, Abdou Mohamed Ali, Basset Maha A A, Pasha Heba Fouad
Abstract excerpt
BackgroundAlterations of B2 adrenergic receptor (β2AR) can modulate the severity of asthma and the response to treatment. Therefore, we aimed to evaluate β2AR gene polymorphism at codons 16 and 27 and their effect on asthma severity and response to treatment in asthmatic children.MethodsCase-control study was conducted on 156 children; 104 of them had bronchial asthma and 52 were healthy children (control group)....
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