Article
Beta2-adrenoceptor polymorphisms predict response to beta2-agonists in children with acute asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Jun 2008
Martin Andrew C, Zhang Guicheng, Rueter Kristina, Khoo Siew-Kim, Bizzintino Joelene, Hayden Catherine M, Geelhoed Gary C, Goldblatt Jack, Laing Ingrid A, Le Souëf Peter N
Abstract excerpt
The aim of this study was to determine the influence of single nucleotide polymorphisms in the beta(2)-adrenoceptor gene, on the response to inhaled beta(2)-agonists in children with acute asthma. We hypothesised that children with polymorphisms that generate enhanced receptor downregulation in v...
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