Article
GSTM1-null and GSTA1-low activity genotypes are associated with enhanced oxidative damage in bladder cancer.
Redox report : communications in free radical research - 1 Jan 2013
Savic-Radojevic Ana, Djukic Tatjana, Simic Tatjana, Pljesa-Ercegovac Marija, Dragicevic Dejan, Pekmezovic Tatjana, Cekerevac Milica, Santric Veljko, Matic Marija
Abstract excerpt
OBJECTIVES: To examine the association between gene variants of the detoxifying and antioxidant enzymes glutathione transferase M1 (GSTM1) and glutathione transferase A1 (GSTA1) and the extent of oxidative damage in patients with transitional cell carcinoma (TCC) of the urinary bladder. METHODS: GSTM1 deletion polymorphism was identified by polymerase chain reaction, and the restriction fragment length...
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