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Article

Fibroblast growth factor receptor-2 mutation analysis in human prostate cancer.

BJU international - 1 Oct 2000

Mehta P, Robson C N, Neal D E, Leung H Y

Abstract excerpt

OBJECTIVE: To assess whether mutations in the hot-spots of the fibroblast growth factor (FGF) receptor-2 gene (FGFR2, exons encoding the IIIa, IIIb, IIIc and transmembrane domain, TMD) are associated with the development of prostate cancer, as the IIIb variant is the specific receptor for FGF7/KGF, an androgen-inducible paracrine factor regulating prostatic growth. Materials and methods Single-strand...

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Source

Identifiers

PMID: 11069376
DOI: 10.1046/j.1464-410x.2000.00893.x

Genes

FGFR2
FGF7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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