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Article

R726L androgen receptor mutation is uncommon in prostate cancer families in the united states.

The Prostate - 1 Mar 2003

Gruber Stephen B, Chen Hong, Tomsho Lynn P, Lee Nana, Perrone Erin E, Cooney Kathleen A

Abstract excerpt

BACKGROUND: A mutation in the androgen receptor (AR) gene, namely AR R726L, was described in 2% of Finnish men with sporadic or familial prostate cancer and was associated with an approximately sixfold increased risk of prostate cancer. We set out to determine the incidence of this mutation in a sample of men with either early-onset and/or familial prostate cancer in the United States. METHODS: Five hundred...

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Identifiers

PMID: 12539229
DOI: 10.1002/pros.10195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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