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Article

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers.

The Prostate - 1 Jan 2013

Chiam Karen, Ryan Natalie K, Ricciardelli Carmela, Day Tanya K, Buchanan Grant, Ochnik Aleksandra M, Murti Krisna, Selth Luke A, Butler Lisa M, Tilley Wayne D, Bianco-Miotto Tina

Abstract excerpt

BACKGROUND: Krüppel-like factor (KLF) 6 is a candidate tumor suppressor gene in prostate cancer, but the mechanisms contributing to its loss of expression are poorly understood. We characterized KLF6 expression and DNA methylation status during prostate tumorigenesis in humans and mice. METHODS: KLF6 expression was assessed in matched human non-malignant (NM) and tumor prostate tissues (n = 22) by quantitative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22782870
DOI: 10.1002/pros.22554

Genes

KLF6

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