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Article

Deletion, mutation, and loss of expression of KLF6 in human prostate cancer.

The American journal of pathology - 1 Apr 2003

Chen Ceshi, Hyytinen Eija-Riitta, Sun Xiaodong, Helin Heikki J, Koivisto Pasi A, Frierson Henry F, Vessella Robert L, Dong Jin-Tang

Abstract excerpt

Kruppel-like factors (KLFs) are a group of transcription factors that appear to be involved in different biological processes including carcinogenesis. In a recent study, KLF6 was reported as a tumor suppressor gene in prostate cancer because of its frequent loss of heterozygosity (LOH) and mutation as well as functional suppression of cell proliferation. Loss of chromosomal locus spanning KLF6 is relatively...

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Identifiers

PMID: 12651626
DOI: 10.1016/S0002-9440(10)63930-2
PMCID: PMC1851229

Genes

KLF6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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