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Article

Effects of pooling mRNA in microarray class comparisons.

Bioinformatics (Oxford, England) - 12 Dec 2004

Shih Joanna H, Michalowska Aleksandra M, Dobbin Kevin, Ye Yumei, Qiu Ting Hu, Green Jeffrey E

Abstract excerpt

MOTIVATION: In microarray experiments investigators sometimes wish to pool RNA samples before labeling and hybridization due to insufficient RNA from each individual sample or to reduce the number of arrays for the purpose of saving cost. The basic assumption of pooling is that the expression of an mRNA molecule in the pool is close to the average expression from individual samples. Recently, a method for...

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PMID: 15247103
DOI: 10.1093/bioinformatics/bth391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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