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Article

Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila.

Annals of the New York Academy of Sciences - 1 Jun 2004

Miwa Satomi, Riyahi Kumars, Partridge Linda, Brand Martin D

Abstract excerpt

The free radical theory of aging proposes that mitochondrial production of reactive oxygen species (ROS) determines the rate of aging. Supporting this hypothesis, longer-lived species produce fewer ROS than shorter-lived ones, and calorically restricted rodents live longer and produce fewer ROS than controls. We studied such correlation in Drosophila melanogaster in caloric restriction and in mutant flies...

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Identifiers

PMID: 15247051
DOI: 10.1196/annals.1297.069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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