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Mitochondrial ROS production correlates with, but does not directly regulate lifespan in drosophila

15 Apr 2010

Abstract excerpt

The Mitochondrial Free Radical Theory of Aging (MFRTA) is currently one of the most widely accepted theories used to explain aging. From MFRTA three basic predictions can be made: long-lived individuals or species should produce fewer mitochondrial Reactive Oxygen Species (mtROS) than short-lived individuals or species; a decrease in mtROS production will increase lifespan; and an increase in mtROS production...

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PMID: 20453260
DOI: 10.18632/aging.100137

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