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Article

Lifespan extension by dietary restriction is not linked to protection against somatic DNA damage in Drosophila melanogaster.

Aging cell - 1 Jun 2009

Edman Ursula, Garcia Ana Maria, Busuttil Rita A, Sorensen Dylan, Lundell Martha, Kapahi Pankaj, Vijg Jan

Abstract excerpt

Dietary restriction (DR) has been shown to robustly extend lifespan in multiple species tested so far. The pro-longevity effect of DR is often ascribed to an increase in cellular defense against somatic damage, most notably damage by reactive oxygen species (ROS), considered a major cause of aging. Especially irreversible damage to DNA, the carrier of genetic information, is considered a critical causal factor in...

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Identifiers

PMID: 19627272
DOI: 10.1111/j.1474-9726.2009.00480.x
PMCID: PMC2917806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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