Article
Low levels of mtDNA deletion mutations in ETS normal fibers from aged rats.
Annals of the New York Academy of Sciences - 1 Jun 2004
Pak Jeong W, Aiken Judd M
Abstract excerpt
The objectives were (1) to determine whether deletion mutations occur in phenotypically normal type I and type II fibers, (2) to quantify the levels of both deletion mutant and wild-type (wt) mtDNA (nondeletion) within single normal fibers containing mutant mtDNA, and (3) to quantify the amount of wt mtDNA in genotypically and phenotypically normal type I and type II fibers. Deletion mutations in normal fibers...
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