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Article

Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Nov 2010

Lemieux Hélène, Vazquez Edwin J, Fujioka Hisashi, Hoppel Charles L

Abstract excerpt

We measured the loss of cardiac mitochondrial function related to aging in males of three rat strains presenting with different longevity and aging phenotypes: the Fischer 344 (F344), the Brown Norway (BN), and the hybrid F344×BN. The F344 rat has a short life span and a ∼45% decrease in coupled...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20801909
DOI: 10.1093/gerona/glq141
PMCID: PMC2981518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20801909-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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