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Article

Mutation and accumulation of p53 related to results of adjuvant therapy of postmenopausal breast cancer patients.

Acta oncologica (Stockholm, Sweden) - 1 Jan 2004

Askmalm Marie Stenmark, Carstensen John, Nordenskjöld Bo, Olsson Birgit, Rutqvist Lars Erik, Skoog Lambert, Stål Olle

Abstract excerpt

p53 protein accumulation and gene mutation have been implicated in resistance to cytotoxic treatment. This study was performed to further assess the predictive value of p53 in breast cancer. Postmenopausal patients were randomized to adjuvant chemotherapy with cyclophosphamide, metothrexate, or 5-fluorouracil (CMF) vs. postoperative radiotherapy. The patients were also randomized to adjuvant tamoxifen vs. no...

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PMID: 15244246
DOI: 10.1080/02841860410029474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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