Article
Predictive and prognostic role of p53 according to tumor phenotype in breast cancer patients treated with preoperative chemotherapy: a single-institution analysis.
The International journal of biological markers - 1 Jan 2000
Guarneri Valentina, Barbieri Elena, Piacentini Federico, Giovannelli Simona, Ficarra Guido, Frassoldati Antonio, Maiorana Antonino, D'Amico Roberto, Conte Pierfranco
Abstract excerpt
INTRODUCTION AND AIMS: The p53 protein is a mediator of the cellular response to DNA damage. The aim of this study was to evaluate the predictive and/or prognostic value of p53 expression in relation to the molecular subtypes of breast cancer in patients treated with preoperative chemotherapy. PATIENTS AND METHODS: Patients with stage II-III breast cancer were included in the study. The expression of p53 was...
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