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Article

SOCS: suppressors of cytokine signalling.

The international journal of biochemistry & cell biology - 1 Oct 1998

Starr R, Hilton D J

Abstract excerpt

Regulation of many aspects of cell behaviour occurs through the interaction of cytokines with specific cell surface receptors, resulting in the activation of cytoplasmic signal transduction pathways. Although cellular responses to cytokines are tightly controlled, few molecules have been identified which are able to switch these signals off. The suppressors of cytokine signalling (SOCS) proteins are a new family...

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PMID: 9785473
DOI: 10.1016/s1357-2725(98)00067-3

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