Article
Mouse mutants for the study of corticotropin-releasing hormone receptor function: development of novel treatment strategies for mood disorders.
Annals of the New York Academy of Sciences - 1 Jun 2004
Keck Martin E, Holsboer Florian, Müller Marianne B
Abstract excerpt
In today's psychiatry there is a great deal of interest in the development of compounds with a novel mechanism of action that diverge from the classical catecholaminergic neurotransmitter system targets. Within the last few years, it has become increasingly evident that the neuroendocrine and behavioral phenotypes of mood and anxiety disorders are at least in part mediated by modulation of corticotropin-releasing...
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