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Article

Genetic mouse models for behavioral analysis through transgenic RNAi technology.

Genes, brain, and behavior - 1 Oct 2008

Delic S, Streif S, Deussing J M, Weber P, Ueffing M, Hölter S M, Wurst W, Kühn R

Abstract excerpt

Pharmacological inhibitors and knockout mice have developed into routine tools to analyze the role of specific genes in behavior. Both strategies have limitations like the availability of inhibitors for only a subset of proteins and the large efforts required to construct specific mouse mutants. The recent emergence of RNA interference (RNAi)-mediated gene silencing provides a fast alternative that can be applied...

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Source

Identifiers

PMID: 18518923
DOI: 10.1111/j.1601-183X.2008.00412.x

Genes

CRHR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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