Article
Xenopus XsalF: anterior neuroectodermal specification by attenuating cellular responsiveness to Wnt signaling.
Developmental cell - 1 Jul 2004
Onai Takayuki, Sasai Noriaki, Matsui Masaru, Sasai Yoshiki
Abstract excerpt
Here we show that XsalF, a frog homolog of the Drosophila homeotic selector spalt, plays an essential role for the forebrain/midbrain determination in Xenopus. XsalF overexpression expands the domain of forebrain/midbrain genes and suppresses midbrain/hindbrain boundary (MHB) markers and anterior hindbrain genes. Loss-of-function studies show that XsalF is essential for the expression of the forebrain/midbrain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
