Article
Widely expressed Af17 is likely not required for embryogenesis, hematopoiesis, and animal survival.
Genesis (New York, N.Y. : 2000) - 1 Dec 2010
Zhang Zhijing, Huang Le, Reisenauer Mary Rose, Wu Hongyu, Chen Lihe, Zhang Yujin, Xia Yang, Zhang Wenzheng
Abstract excerpt
As a putative transcription factor, Af17 may play a role in multiple signaling pathways. However, the Af17 expression profile during development and in adult tissues remains largely uncharacterized. The importance of Af17 function in embryogenesis, hematopoiesis, and animal survival has never been addressed before. Here we report the generation of the first Af17 mutant mouse model and characterization of the Af17...
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