Article
Analysis of cytotoxic T lymphocyte antigen-4 (CTLA-4) exon 1 polymorphism in patients with type 1 diabetes mellitus in a Turkish population.
Journal of pediatric endocrinology & metabolism : JPEM - 1 May 2004
Genc Sermin, Genc Kursad, Sercan Ogun, Kizildag Sefa, Gulay Zeynep, Atay Tuba, Dundar Bumin, Sakizli Meral, Büyükgebiz Atilla
Abstract excerpt
Recent studies have described linkage and association between cytotoxic T-lymphocyte antigen-4 (CTLA-4) gene polymorphism and type 1 diabetes mellitus (DM1) in some ethnic populations, but not others. This finding suggests that CTLA-4 gene association with DM1 may be influenced by the racial composition of the population. Thus, it is important to study the polymorphism of the CTLA-4 gene in different ethnic...
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