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Article

CTLA-4 (+49A/G) polymorphism and type-1 diabetes in Turkish children.

Journal of clinical research in pediatric endocrinology - 1 Jan 2013

Çelmeli Fatih, Türkkahraman Doğa, Özel Deniz, Akçurin Sema, Yegin Olcay

Abstract excerpt

OBJECTIVE: To evaluate the contribution of cytotoxic T-Iymphocyte antigen-4(CTLA-4)+49A/G polymorphism to the susceptibility to type-1 diabetes (T1D) in Turkish children. METHODS: A case-control study was designed to include 91 Turkish children with T1D and 99 healthy controls. CTLA-4 (+99A/G) gene polymorphism typing was done by PCR amplification followed by restriction fragment length polymorphism method....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23367498
DOI: 10.4274/Jcrpe.879
PMCID: PMC3628391

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