Article
Alpha- and beta-adrenergic receptor polymorphisms in hypertensive and normotensive offspring.
Journal of cardiovascular medicine (Hagerstown, Md.) - 1 May 2006
Iacoviello Massimo, Forleo Cinzia, Sorrentino Sandro, Romito Roberta, De Tommasi Elisabetta, Lucarelli Katya, Guida Pietro, Pitzalis Maria Vittoria
Abstract excerpt
BACKGROUND: The offspring of hypertensive families are characterized by higher arterial blood pressure values and a depressed autonomic control of heart rate. The present study aimed to verify whether these differences are associated with a different genotype distribution of functionally relevant polymorphisms of the alpha- and beta-adrenergic receptor (AR) genes. METHODS: We selected 109 age- and sex-matched...
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