Article
Role of Escherichia coli DNA polymerase IV in in vivo replication fidelity.
Journal of bacteriology - 1 Jul 2004
Kuban Wojciech, Jonczyk Piotr, Gawel Damian, Malanowska Karolina, Schaaper Roel M, Fijalkowska Iwona J
Abstract excerpt
We have investigated whether DNA polymerase IV (Pol IV; the dinB gene product) contributes to the error rate of chromosomal DNA replication in Escherichia coli. We compared mutation frequencies in mismatch repair-defective strains that were either dinB positive or dinB deficient, using a series of mutational markers, including lac targets in both orientations on the chromosome. Virtually no contribution of Pol IV...
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