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Article

Role of accessory DNA polymerases in DNA replication in Escherichia coli: analysis of the dnaX36 mutator mutant.

Journal of bacteriology - 1 Mar 2008

Gawel Damian, Pham Phuong T, Fijalkowska Iwona J, Jonczyk Piotr, Schaaper Roel M

Abstract excerpt

The dnaX36(TS) mutant of Escherichia coli confers a distinct mutator phenotype characterized by enhancement of transversion base substitutions and certain (-1) frameshift mutations. Here, we have further investigated the possible mechanism(s) underlying this mutator effect, focusing in particular on the role of the various E. coli DNA polymerases. The dnaX gene encodes the tau subunit of DNA polymerase III (Pol...

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Identifiers

PMID: 18156258
DOI: 10.1128/JB.01463-07
PMCID: PMC2258657

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Source receipt: pubmed, retrieved 7 Sept 2026.

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