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Article

Escherichia coli DNA polymerase IV mutator activity: genetic requirements and mutational specificity.

Journal of bacteriology - 1 Aug 2000

Wagner J, Nohmi T

Abstract excerpt

The dinB gene of Escherichia coli is known to be involved in the untargeted mutagenesis of lambda phage. Recently, we have demonstrated that this damage-inducible and SOS-controlled gene encodes a novel DNA polymerase, DNA Pol IV, which is able to dramatically increase the untargeted mutagenesis of F' plasmid. At the amino acid level, DNA Pol IV shares sequence homologies with E. coli UmuC (DNA Pol V), Rev1p, and...

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Source

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Identifiers

PMID: 10913093
DOI: 10.1128/JB.182.16.4587-4595.2000
PMCID: PMC94631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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