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Article

Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli.

The Journal of biological chemistry - 15 Nov 1993

Schaaper R M

Abstract excerpt

The accuracy by which organisms duplicate their DNA is of considerable interest. At least three mechanisms operate, serially, to secure high fidelity: base selection, exonucleolytic proofreading, and postreplicative mismatch correction. To obtain insights into the efficiency and specificity of these steps in the bacterium Escherichia coli, we have performed DNA sequence analysis of mutations occurring in the...

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Identifiers

PMID: 8226906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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