Article
Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma.
BMC cancer - 1 Jul 2004
Abnet Christian C, Huppi Konrad, Carrera Ana, Armistead David, McKenney Keith, Hu Nan, Tang Ze-Zong, Taylor Philip R, Dawsey Sanford M
Abstract excerpt
BACKGROUND: North central China has some of the highest rates of esophageal squamous cell carcinoma in the world with cumulative mortality surpassing 20%. Mitochondrial DNA (mtDNA) accumulates more mutations than nuclear DNA and because of its high abundance has been proposed as a early detection...
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