Article
Requirement for Dlgh-1 in planar cell polarity and skeletogenesis during vertebrate development.
PloS one - 1 Jan 2013
Rivera Charlene, Simonson Sara J S, Yamben Idella F, Shatadal Shalini, Nguyen Minh M, Beurg Maryline, Lambert Paul F, Griep Anne E
Abstract excerpt
The development of specialized organs is tightly linked to the regulation of cell growth, orientation, migration and adhesion during embryogenesis. In addition, the directed movements of cells and their orientation within the plane of a tissue, termed planar cell polarity (PCP), appear to be crucial for the proper formation of the body plan. In Drosophila embryogenesis, Discs large (dlg) plays a critical role in...
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