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Article

Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity.

Diabetes & metabolism - 1 Apr 2004

Zouari Bouassida K, Chouchane L, Jellouli K, Chérif S, Haddad S, Gabbouj S, Danguir J

Abstract excerpt

OBJECTIVES: Tumor necrosis factor alpha (TNFalpha) is expressed primarily in adipocytes and elevated levels of this cytokine have been linked to obesity and insulin resistance. Several studies have shown statistical evidence of linkage between obesity and the chromosomal region encompassing the TNFalpha gene, suggesting that TNF alpha and/or a nearby gene is involved in the pathogenesis of obesity. Recently we...

Topics

Blood Glucose
Body Mass Index
Body Weight
Diabetes Mellitus
Diabetes Mellitus, Type 2
Female
Genetic Predisposition to Disease
Genotype
Glycated Hemoglobin
HSP70 Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Lipids

Male

Middle Aged

Obesity

Polymerase Chain Reaction

Polymorphism, Genetic

Restriction Mapping

Source

Identifiers

PMID: 15223990
DOI: 10.1016/s1262-3636(07)70104-0

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity.PMID 15223990Read ↗

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