Article
Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumors.
Cancer - 15 Oct 1997
Chouchane L, Ahmed S B, Baccouche S, Remadi S
Abstract excerpt
BACKGROUND: Tumor necrosis factors (TNFs) and heat shock protein 70 (hsp70) are determining factors in immunologic mechanisms to tumor cells. The authors designed a case-controlled study to investigate the potential association of the polymorphisms of TNF-alpha and of hsp70-2 and hsp70-hom genes...
Topics
- Adult
- Alleles
- Breast Neoplasms
- DNA
- DNA, Neoplasm
- Female
- Gastrointestinal Neoplasms
- HSP70 Heat-Shock Proteins
- Haplotypes
- Homozygote
- Humans
- Lymphoma, Non-Hodgkin
- Male
- Middle Aged
- Neoplasms
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Tumor Necrosis Factor-alpha