Article
TLR-2 Germ Line Variants as a Risk for Obesity in Local Pakistani Population.
Archives of medical research - 1 Jun 2022
Shoukat Mehreen, Ullah Rooh, Javaid Maheen, Anas Muhammad, Tariq Mariam, Faryal Rani
Abstract excerpt
BACKGROUND: Obesity is increasing rapidly affecting half billion adult's population. Pathophysiology of obesity involves low grade inflammation sustained by Toll like receptor 2 (TLR-2) the innate immune adapters. This study was conducted for detection and association of TLR-2 gene mutations with obesity. METHODS: In this case-control study 228 individuals with obesity and 228 controls were enrolled based on Body...
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