Article
Genetic variants of tumor necrosis factor-α and its levels: A correlation with dyslipidemia and type 2 diabetes susceptibility.
Clinical nutrition (Edinburgh, Scotland) - 1 Jun 2019
Patel Roma, Palit Sayantani Pramanik, Rathwa Nirali, Ramachandran A V, Begum Rasheedunnisa
Abstract excerpt
BACKGROUND & AIM: Tumor necrosis factor-α (TNF-α) and its genetic variants are implicated in the development of type 2 diabetes (T2D) as a result of systemic inflammation, dyslipidemia, and insulin resistance. The aim of the present study was to investigate i) single nucleotide polymorphisms (SNPs) of TNF-α and its association with altered TNF-α transcript levels and plasma concentrations ii) free fatty acid...
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