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Article

Dark adaptation of rod photoreceptors in normal subjects, and in patients with Stargardt disease and an ABCA4 mutation.

Investigative ophthalmology & visual science - 1 Jul 2004

Kang Derwent Jennifer J, Derlacki Deborah J, Hetling John R, Fishman Gerald A, Birch David G, Grover Sandeep, Stone Edwin M, Pepperberg David R

Abstract excerpt

PURPOSE: Psychophysical and electroretinographic (ERG) studies indicate that patients with Stargardt disease exhibit abnormally slow rod dark adaptation after illumination that bleaches a substantial fraction of rhodopsin. However, relatively little information is available concerning rod recovery in this disease after weaker adapting (i.e., conditioning) light. With the use of a paired-flash ERG method,...

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Source

Identifiers

PMID: 15223829
DOI: 10.1167/iovs.03-1178

Genes

ABCA4
ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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