Rod photoreceptor temporal properties in retinitis pigmentosa.

doi:10.1016/j.exer.2010.12.014

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Article

Rod photoreceptor temporal properties in retinitis pigmentosa.

Experimental eye research - 1 Mar 2011

Wen Yuquan, Locke Kirsten G, Hood Donald C, Birch David G

Abstract excerpt

One of the characteristic signs of retinitis pigmentosa (RP) is the progressive loss of night vision. We have previously shown that the gain of rod photoreceptor activation is moderately reduced in some patients with RP, but this decrease in activation kinetics is not sufficient to account for the night blindness. Recently, single rod recording from animal models of RP showed rods under degeneration remain...

Topics

Adult
Aged
Electroretinography
Humans
Intermediate Filament Proteins
Membrane Glycoproteins
Mutation
Nerve Tissue Proteins
Peripherins
Photic Stimulation
Retinal Rod Photoreceptor Cells
Retinitis Pigmentosa
Rhodopsin
Vision, Ocular

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PMID: 21219898
DOI: 10.1016/j.exer.2010.12.014
PMCID: PMC3057282

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