Article
Abnormal activation and inactivation mechanisms of rod transduction in patients with autosomal dominant retinitis pigmentosa and the pro-23-his mutation.
Investigative ophthalmology & visual science - 1 Jul 1995
Birch D G, Hood D C, Nusinowitz S, Pepperberg D R
Abstract excerpt
PURPOSE: The leading edge of the rod a-wave in normal human subjects can be fit with a computational model of the activation phase of transduction to provide parameters analogous to those obtained from individual photoreceptors. The authors extend this work to the kinetics of recovery after saturating flashes. METHODS: Electroretinograms were recorded from three patients with autosomal dominant retinitis...
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