Article
Abnormal dark adaptation kinetics in autosomal dominant sector retinitis pigmentosa due to rod opsin mutation.
The British journal of ophthalmology - 1 Aug 1992
Moore A T, Fitzke F W, Kemp C M, Arden G B, Keen T J, Inglehearn C F, Bhattacharya S S, Bird A C
Abstract excerpt
The time course of dark adaptation was measured in 10 subjects from three families with autosomal dominant sector retinitis pigmentosa (RP) due to mutations in the first exon of the rod opsin gene. In each subject cone adaptation and the early part of the recovery of rod sensitivity followed the normal time course, but the later phase of rod adaptation was markedly prolonged. The recovery of rod sensitivity is...
Topics
- Adolescent
- Adult
- Aged
- Chromosome Aberrations
- Chromosome Disorders
- Dark Adaptation
- Electroretinography
- Family
- Genes, Dominant
- Humans
- Middle Aged