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Article

Tumor necrosis factor gene polymorphisms and inflammatory response in coronary artery bypass grafting patients.

Scandinavian cardiovascular journal : SCJ - 1 Jun 2004

Westerberg Martin, Bengtsson Anders, Ricksten Anne, Jeppsson Anders

Abstract excerpt

BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha), a key factor in the inflammatory cascade, has been implicated in coronary artery disease. Two biallelic polymorphisms in the TNF gene locus (TNFA at position -308 and TNFB at +252) may influence TNF-alpha production. Individuals with the rare TNFA2 allele or TNFB2 homozygosity have augmented TNF-alpha production. We investigated the genotypes associated with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15223716
DOI: 10.1080/14017430410031795

Genes

TNF
CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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