Article
The -251A>T polymorphism of interleukin-8 is associated with longer mechanical ventilation and hospital staying after coronary surgery.
Cytokine - 1 Jun 2010
Wang Zanxin, Shao Jie, Zhou Qinghua, Liu Jianshi, Zhu Yu, Yang Jie, Wei Minxin
Abstract excerpt
BACKGROUND: Cardiac surgery is associated with inflammatory responses that are known to affect its outcome. The present study was designed to define whether post-operative release of interleukin (IL)-6, 8 and tumor necrosis factor-alpha (TNF-alpha) is related to the presence of a certain allele in functional polymorphism and its relationship to clinical outcome after off-pump coronary artery bypass (OPCAB)....
Topics
- Coronary Artery Bypass, Off-Pump
- Genotype
- Humans
- Interleukin-8
- Interleukins
- Length of Stay
- Logistic Models
- Middle Aged
- Perioperative Care
- Polymorphism, Single Nucleotide
- Respiration, Artificial