Article
Tumor necrosis factor alpha influences the inflammatory response after coronary surgery.
The Annals of thoracic surgery - 1 Jan 2006
Bittar Mohamad N, Carey John A, Barnard James B, Pravica Vera, Deiraniya Abdul K, Yonan Nizar, Hutchinson Ian V
Abstract excerpt
BACKGROUND: A systemic inflammatory response is not uncommonly observed after coronary revascularization. Tumor necrosis factor alpha is one of a number of modulators of this response. A functional polymorphism within the TNFalpha gene at position G-308A has been associated with increased TNFalpha levels. The relationship between predicted TNFalpha genotype and circulating TNFalpha levels in patients undergoing...
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