Tumor necrosis factor alpha influences the inflammatory response after coronary surgery.

doi:10.1016/j.athoracsur.2005.07.037

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Article

Tumor necrosis factor alpha influences the inflammatory response after coronary surgery.

The Annals of thoracic surgery - 1 Jan 2006

Bittar Mohamad N, Carey John A, Barnard James B, Pravica Vera, Deiraniya Abdul K, Yonan Nizar, Hutchinson Ian V

Abstract excerpt

BACKGROUND: A systemic inflammatory response is not uncommonly observed after coronary revascularization. Tumor necrosis factor alpha is one of a number of modulators of this response. A functional polymorphism within the TNFalpha gene at position G-308A has been associated with increased TNFalpha levels. The relationship between predicted TNFalpha genotype and circulating TNFalpha levels in patients undergoing...

Topics

Aged
Cardiopulmonary Bypass
DNA Mutational Analysis
Elective Surgical Procedures
Female
Genetic Predisposition to Disease
Genotype
Humans
Male
Middle Aged
Myocardial Revascularization
Polymerase Chain Reaction
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Postoperative Complications

Risk Factors

Systemic Inflammatory Response Syndrome

Treatment Outcome

Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 16368349
DOI: 10.1016/j.athoracsur.2005.07.037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.