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Article

Genetic polymorphisms of apolipoprotein E4 and tumor necrosis factor beta as predisposing factors for increased inflammatory cytokines after cardiopulmonary bypass.

The Journal of thoracic and cardiovascular surgery - 1 Jul 2004

Grünenfelder Jürg, Umbehr Martin, Plass Andre, Bestmann Lukas, Maly Friedrich E, Zünd Gregor, Turina Marko

Abstract excerpt

OBJECTIVE: Cardiopulmonary bypass induces a rise in cytokines released by activated monocytes. The apolipoprotein E and the tumor necrosis factor beta polymorphisms are risk factors for atherosclerosis. The aim of the study was to investigate whether the genetic variants of apolipoprotein E (APOE...

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Source

Identifiers

PMID: 15224026
DOI: 10.1016/j.jtcvs.2004.02.022

Genes

APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15224026-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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