Article
Comparison of cytochrome P450 2C9 genotyping methods and implications for the clinical laboratory.
Pharmacotherapy - 1 Jun 2004
Aquilante Christina L, Lobmeyer Maximilian T, Langaee Taimour Y, Johnson Julie A
Abstract excerpt
STUDY OBJECTIVE: To compare the accuracy, speed, and cost of two methodologies used for genotyping known variants in the cytochrome P450 (CYP) 2C9 metabolizing enzyme gene. DESIGN: Comparative study. SETTING: University research center. SAMPLES: Fifteen-milliliter mouthwash samples collected from 253 subjects participating in a warfarin pharmacogenomic study. INTERVENTION: Genotyping for the isoleucine-to-leucine...
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